FOODBALL Project Overview
The Food Biomarkers Alliance – FoodBAll – is a JPI-funded, multicentric project aiming to develop strategies for food biomarker discovery and validation, and to identify biomarkers of intake for a range of foods.

This page is maintained as a collaborative effort of numerous experts in the field of food metabolomics. It will provide support for the food metabolome community through the collection of useful information and tools, concepts, current practices and major updates in the field.
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Recent Papers
A selection of recent papers on the food metabolome and identification/validation of dietary biomarkers.
  • Are Metabolic Signatures Mediating the Relationship between Lifestyle Factors and Hepatocellular Carcinoma Risk? Results from a Nested Case–Control Study in EPIC
  • Nutrimetabolomics: integrating metabolomics in nutrition to disentangle intake of animal-based foods
  • Diabetes and branched‐chain amino acids: What is the link?
  • Urinary Metabolites Associated with Blood Pressure on a Low- or High-Sodium Diet
  • Critical review of reporting of the data analysis step in metabolomics
  • The analytical process to search for metabolomics biomarkers
  • Recommended strategies for spectral processing and post-processing of 1D 1H-NMR data of biofluids with a particular focus on urine
  • 1H NMR-based metabolomics reveals the effect of maternal habitual dietary patterns on human amniotic fluid profile
  • Effects of a 12-week high-α-linolenic acid intervention on EPA and DHA concentrations in red blood cells and plasma oxylipin pattern in subjects with a low EPA and DHA status
  • Use of Metabolomics in Improving Assessment of Dietary Intake
  • Urinary Metabolomics Profiles Associated to Bovine Meat Ingestion in Humans
  • Effect of Dietary Counseling on a Comprehensive Metabolic Profile from Childhood to Adulthood
  • The effect of coffee intake on lysophosphatidylcholines: A targeted metabolomic approach
  • Metabolomics of postprandial plasma alterations: a comprehensive Japanese study
  • Joint Data Analysis in Nutritional Epidemiology: Identification of Observational Studies and Minimal Requirements
  • Guidelines for Biomarker of Food Intake Reviews (BFIRev): how to conduct an extensive literature search for biomarker of food intake discovery
  • nmrML: A Community Supported Open Data Standard for the Description, Storage, and Exchange of NMR Data
  • High Resolution Mass Spectrometric Analysis of Secoiridoids and Metabolites as Biomarkers of Acute Olive Oil Intake—An Approach to Study Interindividual Variability in Humans
  • Validation of the Brazilian Healthy Eating Index-Revised Using Biomarkers in Children and Adolescents
  • GC-MS Based Metabolomics and NMR Spectroscopy Investigation of Food Intake Biomarkers for Milk and Cheese in Serum of Healthy Humans
  • HMDB 4.0: the human metabolome database for 2018
  • Biomarkers of cereal food intake
  • Biomarkers of meat and seafood intake: An extensive literature review
  • Biomarkers of moderate alcohol intake and alcoholic beverages: a systematic literature review
  • Biomarkers of seaweed intake
  • Biomarkers of intake for tropical fruits
  • Biomarkers of tuber intake
  • BioTransformer: A comprehensive computational tool for small molecule metabolism prediction and metabolite identification
  • BioTransformer 3.0—a web server for accurately predicting metabolic transformation products
  • CFM-ID 3.0: Significantly improved ESI-MS/MS prediction and compound identification
  • CFM-ID 4.0: More accurate ESI-MS/MS spectral prediction and compound identification
  • Characterization of the human exposome by a comprehensive and quantitative large-scale multianalyte metabolomics platform
  • Dietary biomarkers—an update on their validity and applicability in epidemiological studies
  • Discovery of urinary biomarkers of spinach consumption using untargeted LC-MS metabolomics in a human intervention trial
  • Discovery and validation of banana intake biomarkers using untargeted metabolomics in human intervention and cross-sectional studies
  • Exposome-Explorer 2.0: an update incorporating candidate dietary biomarkers and dietary associations with cancer risk
  • FOBI: an ontology to represent food intake data and associate it with metabolomic data
  • Food intake biomarkers for berries and grapes
  • Food intake biomarkers for green leafy vegetables, bulb vegetables, and stem vegetables: A review
  • Herbs and spices- biomarkers of intake based on human intervention studies – a systematic review
  • MarkerDB: an online database of molecular biomarkers
  • Metabolomic-based approach to identify biomarkers of apple intake
  • Metabolomic based approach to identify biomarkers of broccoli intake
  • A metabolomic study of biomarkers of habitual coffee intake in four European countries
  • Metabolomics for investigating physiological and pathophysiological processes
  • Nutrimetabolomics: An integrative action for metabolomic analyses in human nutritional studies
  • Syringol metabolites as new biomarkers for smoked meat intake
  • A comprehensive targeted metabolomics assay for crop plant sample analysis
  • Robust markers of coffee consumption identified among the volatile organic compounds in human urine
    • Strawberries