FOODBALL Project Overview

The Food Biomarkers AllianceFoodBAll – is a JPI-funded, multicentric project aiming to develop strategies for food biomarker discovery and validation, and to identify biomarkers of intake for a range of foods.

This page is maintained as a collaborative effort of numerous experts in the field of food metabolomics. It will provide support for the food metabolome community through the collection of useful information and tools, concepts, current practices and major updates in the field.
Recent Papers

A selection of recent papers on the food metabolome and identification/validation of dietary biomarkers.

First Half of 2017

  • The role of metabolomics in determination of new dietary biomarkers
  • The translation of lipid profiles to nutritional biomarkers in the study of infant metabolism.
  • Within-person reproducibility and sensitivity to dietary change of C15:0 and C17:0 levels in dried blood spots: data from the European Food4Me Study.
  • Correspondence of folate dietary intake and biomarker data.
  • One (small) step towards precision nutrition by use of metabolomics.
  • The nutritional metabolomics crossroads: how to ensure success for dietary biomarkers.
  • Metabolic Phenotyping of Diet and Dietary Intake.
  • Determination of oleanolic acid in human plasma and its association with olive oil intake in healthy Spanish adults within the EPIC Spain cohort study.
  • Validating polyphenol intake estimates from a food-frequency questionnaire by using repeated 24-h dietary recalls and a unique method-of-triads approach with 2 biomarkers.
  • A Systematic Review of Technology-Based Dietary Intake Assessment Validation Studies That Include Carotenoid Biomarkers.
  • Untargeted metabolomic analysis of human serum samples associated with different levels of red meat consumption: A possible indicator of type 2 diabetes?
  • Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: an overview.
  • A metabolomic study of biomarkers of meat and fish intake.
  • Whole-Grain Intake, Reflected by Dietary Records and Biomarkers, Is Inversely Associated with Circulating Insulin and Other Cardiometabolic Markers in 8-to 11-Year-Old Children.
  • Influence of an intervention targeting a reduction in sugary beverage intake on the delta13C sugar intake biomarker in a predominantly obese, health-disparate sample.
  • Urinary Biomarkers of Whole Grain Wheat Intake Identified by Non-targeted and Targeted Metabolomics Approaches.
  • Relying on biomarkers for intake assessment in nutrition.
  • Metabolomic profiles as reliable biomarkers of dietary composition.
  • Ethylglucuronide in the urine as a marker of alcohol consumption during pregnancy: Comparison with four alcohol screening questionnaires.
  • Fatty Acids in Membranes as Homeostatic, Metabolic and Nutritional Biomarkers: Recent Advancements in Analytics and Diagnostics.
  • Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial.
  • Metabolomics as a tool in the identification of dietary biomarkers.
  • Detecting Beer Intake by Unique Metabolite Patterns.
  • Detecting Beer Intake by Unique Metabolite Patterns.
  • Reprint of Standardisation and use of the alcohol biomarker carbohydrate-deficient transferrin (CDT).
  • Validation study of a food frequency questionnaire for the measurement of food consumption in polyphenols: use of a urinary bioamarker. Preliminary results.
  • Foods contributing to vitamin B6, folate, and vitamin B12 intakes and biomarkers status in European adolescents: The HELENA study.
  • Relation of rice intake and biomarkers of cadmium for general population in Korea.
  • Plasma 3-Methylhistidine as Marker for Muscle Status: Impact of Diet and Meat Intervention.
  • Dietary biomarker evaluation in a controlled feeding study in women from the Women's Health Initiative cohort.
  • High-Throughput Quantitation of Proline Betaine in Foods and Suitability as a Valid Biomarker for Citrus Consumption.
  • Application of Liquid Chromatography Tandem Mass Spectrometry To Determine Urinary Concentrations of Five Commonly Used Low Calorie Sweeteners: A Novel Biomarker Approach for Assessing Recent Intakes?
  • Quality of food-frequency questionnaire validation studies in the dietary assessment of children aged 12 to 36 months: a systematic literature review.
  • Urinary H-1 Nuclear Magnetic Resonance Metabolomic Fingerprinting Reveals Biomarkers of Pulse Consumption Related to Energy-Metabolism Modulation in a Subcohort from the PREDIMED study.
  • Dietary, anthropometric, and biochemical factors influencing plasma choline, carnitine, trimethylamine, and trimethylamine-N-oxide concentrations.
  • Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations.
  • Applying recovery biomarkers to calibrate self-report measures of sodium and potassium in the Hispanic Community Health Study/Study of Latinos.
  • Exposome-Explorer: a manually-curated database on biomarkers of exposure to dietary and environmental factors.
  • Lessons on dietary biomarkers from twin studies.
  • The role of metabolomics in determination of new dietary biomarkers.
  • Nutritional biomarkers: current view and future perspectives.
  • Relative validation of 24-h urinary hippuric acid excretion as a biomarker for dietary flavonoid intake from fruit and vegetables in healthy adolescents.
  • Cadmium and Alzheimer's disease mortality in US adults: Updated evidence with a urinary biomarker and extended follow-up time.
  • Challenges and Lessons Learned in Generating and Interpreting NHANES Nutritional Biomarker Data.
  • Identifying biomarkers of dietary patterns by using metabolomics.
  • Identifying biomarkers of dietary patterns by using metabolomics.
  • Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers.
  • Metabolic profiles from two different breakfast meals characterized by H-1 NMR-based metabolomics.
  • A serum metabolomics-driven approach predicts orange juice consumption and its impact on oxidative stress and inflammation in subjects from the BIONAOS study.
  • Milk fat biomarkers and cardiometabolic disease.
  • Identification and quantification of even and odd chained 5-n alkylresorcinols, branched chain-alkylresorcinols and methylalkylresorcinols in Quinoa (Chenopodium quinoa).
  • Short-term biomarkers of apple consumption.
  • A Validation Study of an Interviewer-Administered Short Food Frequency Questionnaire in Assessing Dietary Vitamin D and Calcium Intake in Swedish Children.
  • Dietary long-chain fatty acids and carbohydrate biomarker evaluation in a controlled feeding study in participants from the Women's Health Initiative cohort.
  • Reproducibility of urinary biomarkers in multiple 24-h urine samples.
  • Sensitive and precise monitoring of phosphatidylethanol in human blood as a biomarker for alcohol intake by ultrasound-assisted dispersive liquid-liquid microextraction combined with liquid chromatography tandem mass spectrometry.
  • Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate.
  • Novel urinary alkylresorcinol metabolites as biomarkers of whole grain intake in free-living Swedish adults.
  • Use of biomarkers to assess fruit and vegetable intake.
  • Evaluation of urinary resveratrol as a biomarker of dietary resveratrol intake in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
  • Biomarker-calibrated nutrient intake and healthy diet index associations with mortality risks among older and frail women from the Women's Health Initiative.
  • Validity of the Food Frequency Questionnaire Assessing the Folate Intake in Women of Reproductive Age Living in a Country without Food Fortification: Application of the Method of Triads.
  • Untargeted metabolomics of colonic digests reveals kynurenine pathway metabolites, dityrosine and 3-dehydroxycarnitine as red versus white meat discriminating metabolites
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